Peptide Synthesis

Peptide Synthesis

Peptide Synthesis

  • Peptide Synthesis: Application
  • Availability: Source Available
  • Contact Info: 9341240792 |
  • Factory Info: 67CF+VFW, Hosahalli, Karnataka 562132

NMR spectroscopy is an important tool in peptide synthesis for analyzing the purity, identity, and conformation of synthesized peptides. In order to obtain reliable NMR data, it is important to use appropriate solvents that will not interfere with the peptide signal or produce broad background signals.

Common solvents used in NMR spectroscopy include deuterated water (D2O), deuterated dimethyl sulfoxide (DMSO-d6), deuterated acetonitrile (CD3CN), and deuterated chloroform (CDCl3). However, these solvents may not be suitable for all peptides, as they can have varying levels of solubility and stability depending on the peptide sequence and the presence of certain functional groups.

For peptides containing acidic or basic amino acids, it may be necessary to adjust the pH of the solvent to optimize solubility and minimize aggregation. In some cases, special solvents or solvent mixtures may be required to dissolve and stabilize the peptide.Synmr specializes in solvents for peptide synthesis and can provide tailor-made solutions to your every need.

In addition, care must be taken to avoid contamination of the sample with impurities or other compounds that may interfere with the NMR signal. It is important to use high-purity solvents and to properly clean and dry NMR tubes and other equipment.

Overall, the choice of NMR solvent in peptide synthesis depends on the properties of the peptide being analyzed and the desired NMR experiment. The appropriate solvent should be chosen to optimize solubility and minimize interference with the peptide signal, while also ensuring high-quality NMR data.

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